Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064369 | 0.84 | EPHX2 (0.44) | EPHX2EPHX1ALDH1A1HTTPOLB | |
| SCHEMBL3065184 | 0.83 | EPHX2 (0.38) | EPHX2EPHX1SIGMAR1HTTPOLB | |
| SCHEMBL3068765 | 0.83 | EPHX1 (0.46) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL3068816 | 0.82 | EPHX2 (0.60) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL3071718 | 0.82 | EPHX2 (0.43) | EPHX2EPHX1 | |
| SCHEMBL3069016 | 0.80 | EPHX2 (0.39) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL3065282 | 0.80 | EPHX1 (0.38) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL1605302 | 0.80 | EPHX2 (0.41) | EPHX2EPHX1 | |
| SCHEMBL3064492 | 0.79 | PKM (0.35) | EPHX2EPHX1ALDH1A1TSHRHTT | |
| SCHEMBL3064490 | 0.79 | EPHX2 (0.47) | EPHX2EPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8245687-A | — | — | None | — | — | JP | disclosed |
| JP-H08245687-A | N-MONOSUBSTITUTED ADAMANTYL/NORBORNANYL-17-BETA-CARBAMIDE OF 3-CARBOXY-ANDROST-3,5-DIENE AS TESTOSTERONE 5-ALFA-REDUCTASE INHIBITOR | MERCK & CO INC | 1996-09-24 | — | — | JP | disclosed |