Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519734 | 0.74 | TSHR (0.35) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10812173 | 0.74 | TSHR (0.31) | TSHRNFKB1CYP2C19 | |
| SCHEMBL9860220 | 0.70 | TSHR (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL5081781 | 0.67 | — | — | |
| Pempidine SCHEMBL217663 | 0.65 | TSHR (0.58) | TSHRNFKB1CYP2C19 | |
| Pempidine SCHEMBL4798468 | 0.65 | TSHR (0.58) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11453005 | 0.65 | TSHR (0.36) | TSHRNFKB1CYP2C19 | |
| SCHEMBL15698088 | 0.63 | TSHR (0.31) | TSHRNFKB1CYP2C19 | |
| SCHEMBL18798641 | 0.63 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL5441085 | 0.63 | TSHR (0.34) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457331-B1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA (JP) | 1996-11-20 | — | — | EP | claimed |
| US-5185347-A | PIPERIDINE COMPOUNDS AND ANTIULCER COMPOSITION CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1993-02-09 | — | — | US | claimed |
| EP-0457331-A1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1991-11-21 | — | — | EP | claimed |
| US-4104380-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4076937-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | claimed |
| JP-4021679-A | — | — | None | — | — | JP | disclosed |
| EP-0457331-B1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA (JP) | 1996-11-20 | — | — | EP | disclosed |
| US-5185347-A | PIPERIDINE COMPOUNDS AND ANTIULCER COMPOSITION CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5185347-A | PIPERIDINE COMPOUNDS AND ANTIULCER COMPOSITION CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| JP-H0421679-A | PIPERIDINE DERIVATIVE AND ANTIULCER AGENT WITH THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 1992-01-24 | — | — | JP | disclosed |
| EP-0457331-A1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| EP-0457331-A1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |