⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7086983 | 0.59 | — | — | |
| SCHEMBL322046 | 0.55 | — | — | |
| SCHEMBL28070553 | 0.50 | CHRM5 (0.40) | — | |
| SCHEMBL8792684 | 0.49 | ANPEP (0.36) | — | |
| SCHEMBL27956776 | 0.48 | — | — | |
| SCHEMBL5376368 | 0.48 | — | — | |
| SCHEMBL19596989 | 0.48 | — | — | |
| Iodide SCHEMBL11444291 | 0.48 | — | — | |
| SCHEMBL5144692 | 0.48 | — | — | |
| SCHEMBL27808607 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296498-A | Guanidine compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | claimed |
| US-5494934-A | ANTIDEPRESSANTS, HYPOTENSIVE AGENTS | ADIR ET COMPAGNIE (FR) | 1996-02-27 | — | — | US | disclosed |
| US-5296498-A | Guanidine compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| EP-0488897-A1 | New guanidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-06-03 | — | — | EP | disclosed |