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Sugi Predict / Compounds / SCHEMBL9011680

SCHEMBL9011680

SCHEMBL9011680

CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)CNC(=O)OCc2ccccc2)c1=O)(O[SiH](C)C)C(C(C)(C)C)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 20/20 0.55
▸ CTRC Q99895 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7276063 0.94 ELANE (0.62) ELANECTRC
SCHEMBL7277026 0.89 ELANE (0.59) ELANECTRC
SCHEMBL9011657 0.89 ELANE (0.65) ELANECTRC
SCHEMBL7276483 0.88 ELANE (0.59) ELANECTRC
SCHEMBL7286150 0.88 ELANE (0.65) ELANECTRC
SCHEMBL7283501 0.87 ELANE (0.60) ELANECTRC
SCHEMBL7280564 0.86 ELANE (0.61) ELANECTRC
SCHEMBL8994526 0.85 ELANE (0.58) ELANECTRC
SCHEMBL7274478 0.85 ELANE (0.65) ELANECTRC
SCHEMBL9011660 0.84 ELANE (0.57) ELANECTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521179-A Heterocyclic amides ZENECA LIMITED (GB) 1996-05-28 — — US disclosed