Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775949 | 0.98 | HDAC2 (0.47) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL7907118 | 0.98 | HDAC2 (0.47) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5075350 | 0.94 | HDAC2 (0.47) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL28109818 | 0.92 | HDAC2 (0.48) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL8138563 | 0.81 | KMT2A (0.39) | HDAC2HDAC4HDAC8HDAC6ALDH1A1 | |
| SCHEMBL8429199 | 0.79 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL166015 | 0.79 | HDAC4 (0.41) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL20440725 | 0.79 | HDAC4 (0.41) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL24506981 | 0.79 | HDAC4 (0.40) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL8140023 | 0.78 | KDM4E (0.39) | HDAC2HDAC4HDAC8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028804-A | Alicyclic epoxy resin for semiconductor pouring sealant and synthetic method thereof | 深圳市恒纬祥科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-5525506-A | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5238848-A | Cultures for production of avermectins | PFIZER INC (US) | 1993-08-24 | — | — | US | disclosed |
| US-5077278-A | Parasiticides | PFIZER INC. (US) | 1991-12-31 | — | — | US | disclosed |