Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | TMPRSS11D | O60235 | 8/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012364 | 0.89 | ACE (0.46) | ACEACE2F2PRCPTMPRSS11D | |
| SCHEMBL9012556 | 0.89 | ACE (0.46) | ACEACE2F2PRCPTMPRSS11D | |
| SCHEMBL9012094 | 0.89 | ACE (0.46) | ACEACE2F2PRCPTMPRSS11D | |
| SCHEMBL9012560 | 0.89 | ACE (0.46) | ACEACE2F2PRCPTMPRSS11D | |
| SCHEMBL9012022 | 0.88 | ACE (0.45) | ACEACE2F2PRCPTMPRSS11D | |
| SCHEMBL9012014 | 0.88 | ACE (0.45) | ACEACE2F2PRCPTMPRSS11D | |
| SCHEMBL9086574 | 0.87 | F2 (0.51) | ACEF2TMPRSS11DF10PLG | |
| SCHEMBL9012454 | 0.87 | F2 (0.48) | ACEACE2F2TMPRSS11DF10 | |
| SCHEMBL9012445 | 0.87 | F2 (0.48) | ACEACE2F2TMPRSS11DF10 | |
| SCHEMBL9012260 | 0.86 | F2 (0.47) | ACEACE2F2PRCPTMPRSS11D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |