Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21991349 | 0.79 | TSHR (0.55) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL9011774 | 0.77 | TSHR (0.61) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL19121175 | 0.75 | TSHR (0.47) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL1158620 | 0.75 | ADRB2 (0.54) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL9248942 | 0.75 | TSHR (0.61) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL23605975 | 0.75 | CYP2C9 (0.54) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL21991995 | 0.74 | SMN1; SMN2 (0.51) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL21992000 | 0.74 | TSHR (0.49) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL9011815 | 0.74 | CYP2C9 (0.50) | CYP2C9TSHRTDP1PPARASMN1; SMN2 | |
| SCHEMBL9011956 | 0.74 | TSHR (0.60) | CYP2C9TSHRTDP1PPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530145-A | ANTICHOLESTEROL AGENTS | SYN-TECH CHEM & PHARM CO., LTD. (TW) | 1996-06-25 | — | — | US | disclosed |