Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cinnamic Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Alcohol SCHEMBL28289701 | 1.00 | PAM (0.52) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL39220 | 0.93 | PAM (0.58) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL28583889 | 0.93 | PAM (0.58) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL891462 | 0.93 | PAM (0.58) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL39219 | 0.93 | PAM (0.58) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL4175503 | 0.93 | PAM (0.58) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL27887623 | 0.93 | PAM (0.58) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL28671092 | 0.91 | PAM (0.56) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL28671087 | 0.91 | PAM (0.56) | PAMHTR2AIDO1ALDH1A1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL27879151 | 0.91 | PAM (0.56) | PAMHTR2AIDO1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111424006-B | Recombinant cell and application thereof in synthesizing alpha, beta-unsaturated aldehyde | 浙江工业大学 | 2022-04-19 | — | — | CN | disclosed |
| US-11062794-B2 | Olfactory signature and odorant mixture having the same | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-07-13 | — | — | US | disclosed |
| CN-111424006-A | Recombinant cell and application thereof in synthesizing α -unsaturated aldehyde | 浙江工业大学 | 2020-07-17 | — | — | CN | disclosed |
| US-20180253534-A1 | OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2018-09-06 | — | — | US | disclosed |
| EP-3365418-A2 | PARTICLES FOR MALODOR REDUCTION | The Procter and Gamble Company (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-3325022-A1 | WATER-BASED FRAGRANCE COMPOSITION, FRAGRANCE DELIVERY DEVICE, AND METHOD OF PROVIDING A LONG-LASTING SCENT | S.C. Johnson & Son, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |
| EP-3307394-A1 | FRAGRANCE FIXATIVES AND COMPOSITIONS COMPRISING THEREOF | The Procter and Gamble Company (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3307231-A1 | FRAGRANCE COMPOSITIONS AND USES THEREOF | The Procter and Gamble Company (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3307393-A1 | FRAGRANCE COMPOSITION | The Procter and Gamble Company (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2017158497-A1 | HYDROPHOBICALLY MODIFIED UREA ETHERS AS STRUCTURANTS FOR HYDROPHOBIC SYSTEMS | PROCTER & GAMBLE INERNATIONAL OPERATIONS SA (CH) | 2017-09-21 | — | — | WO | disclosed |
| US-20100104525-A1 | USE OF FRAGRANCE COMPOSITIONS FOR THE PREVENTION OF THE DEVELOPMENT OF INDOLE BASE MALODOURS FROM FECAL AND URINE BASED SOILS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| WO-2009117621-A1 | PEST CONTROL COMPOSITIONS AND METHODS | TYRATECH, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| US-20080032912-A1 | Use of fragrance compositions for the prevention of the development of indole base malodours from fecal and urine based soils | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1884251-A1 | Use of fragrance compositions for the prevention of the development of indole based malodours from faecal and urine based soils | Takasago International Corporation (JP) | 2008-02-06 | — | — | EP | disclosed |
| EP-1622915-A1 | FRAGRANCE COMPOSITIONS COMPRISING BENZO [4,5]THIENO[3,2-B] PYRAN-2-ONE | Flexitral, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004092182-A1 | FRAGRANCE COMPOSITIONS COMPRISING BENZO[4,5]THIENO[3,2-B]PYRAN-2-ONE | FLEXITRAL, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| EP-1458666-A1 | IMPROVED AROMACHEMICALS | Flexitral Inc. (US) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053887-A1 | A METHOD FOR INCREASING THE STABILITY AND INTENSITY OF ODORANT MOLECULES | FLEXITRAL, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| WO-2003053902-A1 | IMPROVED AROMACHEMICALS | FLEXITRAL, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| US-5129951-A | Exposure to benzaldehyde, salicylaldehyde, cinnamaldehyde, hydrocinnamaldehyde, thymol | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1992-07-14 | — | — | US | disclosed |