Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012270 | 1.00 | F2 (0.48) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9011972 | 0.83 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9011989 | 0.83 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012287 | 0.83 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012276 | 0.83 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012279 | 0.83 | F2 (0.53) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012387 | 0.82 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012394 | 0.82 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012131 | 0.82 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL9012117 | 0.82 | F2 (0.39) | F2PRSS1PRSS2PRSS3CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |