Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 14/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820671 | 0.91 | F2 (0.43) | F2PRSS1ACECMA1 | |
| SCHEMBL9086586 | 0.90 | F2 (0.51) | F2PRSS1ACECMA1 | |
| SCHEMBL9085792 | 0.88 | F2 (0.49) | F2PRSS1ACECMA1 | |
| SCHEMBL9073832 | 0.86 | F2 (0.54) | F2PRSS1ACECMA1 | |
| SCHEMBL7346760 | 0.86 | F2 (0.54) | F2PRSS1ACECMA1 | |
| SCHEMBL9088440 | 0.85 | F2 (0.48) | F2PRSS1ACECMA1 | |
| SCHEMBL9012606 | 0.83 | F2 (0.48) | F2PRSS1ACECMA1 | |
| SCHEMBL9012125 | 0.83 | F2 (0.48) | F2PRSS1ACECMA1 | |
| SCHEMBL9012551 | 0.83 | F2 (0.45) | F2PRSS1ACECMA1 | |
| SCHEMBL9012544 | 0.83 | F2 (0.45) | F2PRSS1ACECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |