Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 7/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9087970 | 0.92 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9086586 | 0.91 | F2 (0.51) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9085792 | 0.89 | F2 (0.49) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL7346760 | 0.89 | F2 (0.54) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9073832 | 0.89 | F2 (0.54) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9012533 | 0.85 | F2 (0.49) | F2CMA1PRSS1ACE | |
| SCHEMBL9088429 | 0.84 | F2 (0.49) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9012310 | 0.82 | F2 (0.55) | F2CMA1PRSS1ACEACE2 | |
| SCHEMBL7589201 | 0.82 | F2 (0.70) | F2PRSS1 | |
| SCHEMBL9085068 | 0.82 | F2 (0.50) | F2PRSS1PRSS2PRSS3ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686642-A2 | Modified guanidino and amidino thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-13 | — | — | EP | claimed |
| US-5561146-A | Modified guanidino and amidino thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-01 | — | — | US | disclosed |