SCHEMBL9012679

SCHEMBL9012679

C1=CCC2(C1)CCCO2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3623472 0.85
SCHEMBL5296444 0.79 KCNH2 (0.30)
SCHEMBL17368831 0.76 CYP11B1 (0.33)
SCHEMBL127016 0.76
SCHEMBL126707 0.76
SCHEMBL126686 0.76
SCHEMBL320777 0.73 KCNH2 (0.33)
SCHEMBL1811309 0.73 KCNH2 (0.33)
SCHEMBL3505574 0.73 KCNH2 (0.33)
SCHEMBL27426090 0.73 CYP11B1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127539-A1 FUNCTIONALIZED LINEAR AND CYCLIC POLYOLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-05-10 US disclosed
US-9890239-B2 Functionalized linear and cyclic polyolefins CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-02-13 US disclosed
EP-3107898-A1 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS Takeda Pharmaceutical Company Limited (JP) 2016-12-28 EP disclosed
US-20160215089-A1 FUNCTIONALIZED LINEAR AND CYCLIC POLYOLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-07-28 US disclosed
WO-2015124932-A1 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS TAKEDA CAMBRIDGE LIMITED (GB) 2015-08-27 WO disclosed
EP-0743938-A1 SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-11-27 EP disclosed
WO-1995021817-A1 SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-08-17 WO disclosed