Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811309 | 1.00 | KCNH2 (0.33) | KCNH2CYP11B1CYP11B2 | |
| SCHEMBL3505574 | 1.00 | KCNH2 (0.33) | KCNH2CYP11B1CYP11B2 | |
| SCHEMBL126707 | 0.97 | — | — | |
| SCHEMBL465080 | 0.93 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL21844963 | 0.93 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL16878094 | 0.93 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL26362145 | 0.93 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL16877770 | 0.90 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL16878665 | 0.90 | — | — | |
| SCHEMBL16878311 | 0.90 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076059-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | WO | claimed |
| CN-119053598-A | Substituted 7- (pyrimidin-4-yl) quinolin-4 (1H) -one compounds as cyclin dependent kinase inhibitors | 百济神州有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118302423-A | Amine compound and use thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-07-05 | — | — | CN | claimed |
| WO-2024121262-A1 | INSECTICIDAL COMPOUND BASED ON PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-13 | — | — | WO | claimed |
| WO-2024121264-A1 | INSECTICIDAL COMPOUND BASED ON PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-13 | — | — | WO | claimed |
| US-20040254158-A1 | Anticoagulants; atherosclerosis; strokes; thrombosis; cardiovascular disorders | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-16 | — | — | US | claimed |
| JP-2001501203-A | — | — | 2001-01-30 | — | — | JP | claimed |
| EP-0929554-A1 | SPIRO-AZACYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013369-A1 | SPIRO-AZACYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1998-04-02 | — | — | WO | claimed |
| WO-2026101971-A2 | EGFR INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-12612395-B2 | Rocaglate derivatives and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2026-04-28 | — | — | US | disclosed |
| US-20260091042-A1 | AQUEOUS PHARMACEUTICAL FORMULATION OF HYDROCORTISONE SODIUM PHOSPHATE AND MONOTHIOGLYCEROL | ANTARES PHARMA, INC. (US) | 2026-04-02 | — | — | US | disclosed |
| US-20260078103-A1 | ISOQUINOLONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4705308-A1 | EGFR INHIBITORS FOR TREATING DISEASE | Blossomhill Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |
| US-4602933-A | Phenylurea herbicides | SHELL OIL COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| US-4602934-A | Anilide herbicides | SHELL OIL COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| US-4537702-A | Perfume and flavoring compositions, perfumed articles and materials, and flavored food products containing an oxaspirodecadiene derivative as the essential compound, as well as the oxaspiro[4.5]decadiene derivative per se | NAARDEN INTERNATIONAL N.V. (NL) | 1985-08-27 | — | — | US | disclosed |
| US-RE30574-E | PREEMERGENT AND POSTEMERGENT | SHELL OIL COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4116669-A | Herbicidal tetrahydrofuran derivatives | SHELL OIL COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254158-A1 | Anticoagulants; atherosclerosis; strokes; thrombosis; cardiovascular disorders | SERPINC1, PCSK9, PLAT | KCNH2 991/4885CYP11B1 475/4885CYP11B2 766/4885 |
| US-12612395-B2 | Rocaglate derivatives and uses thereof | GLRB, SRR, HCAR3 | KCNH2 2356/4885CYP11B1 1414/4885CYP11B2 1371/4885 |
| US-20260078103-A1 | ISOQUINOLONES AS PI3K INHIBITORS | PIK3R5, PIK3R4, PIK3CA | KCNH2 1543/4885CYP11B1 186/4885CYP11B2 375/4885 |
| US-20260091042-A1 | AQUEOUS PHARMACEUTICAL FORMULATION OF HYDROCORTISONE SODIUM PHOSPHATE AND MONOTHIOGLYCEROL | NR3C1, HSD11B2, NR3C2 | KCNH2 3436/4885CYP11B1 46/4885CYP11B2 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.