Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107962 | 0.91 | SERPINE1 (0.64) | KMT2AMEN1HPGDPOLBSERPINE1 | |
| SCHEMBL12217821 | 0.87 | KMT2A (0.60) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL6345968 | 0.85 | HPGD (0.75) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL12285142 | 0.84 | EPHX2 (0.54) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL10724841 | 0.83 | POLB (0.81) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL14661768 | 0.83 | POLB (0.65) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL15066106 | 0.83 | KMT2A (0.56) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL4465213 | 0.82 | HPGD (0.68) | HPGDTSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20449044 | 0.82 | HPGD (0.87) | KMT2AMEN1HPGDTSHRPOLB | |
| SCHEMBL12218522 | 0.82 | KMT2A (0.61) | KMT2AMEN1HPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532354-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5401734-A | MICROBIOCIDES | FUJISAWA PHAMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| CN-1025737-C | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-24 | — | — | CN | disclosed |
| US-5244890-A | Treatment of infectious diseases | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| CN-1038814-A | Cephem compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1990-01-17 | — | — | CN | disclosed |
| EP-0345671-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |