Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012838 | 0.84 | KMT2A (0.64) | POLBHPGDALOX15KMT2AMEN1 | |
| SCHEMBL14409686 | 0.82 | ALDH1A1 (0.60) | EPHX2POLBHPGDALOX15KMT2A | |
| SCHEMBL12128812 | 0.81 | EPHX2 (0.79) | EPHX2POLBHPGDALOX15KMT2A | |
| SCHEMBL12128814 | 0.79 | HPGD (0.61) | POLBHPGDKMT2AMEN1CYP1A2 | |
| SCHEMBL10724841 | 0.78 | POLB (0.81) | EPHX2POLBHPGDALOX15KMT2A | |
| SCHEMBL27998048 | 0.78 | GRM5 (0.58) | EPHX2POLBHPGDALOX15KMT2A | |
| SCHEMBL21551794 | 0.77 | POLB (0.65) | EPHX2POLBHPGDALOX15KMT2A | |
| SCHEMBL27997779 | 0.77 | GRM5 (0.54) | EPHX2POLBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2473996 | 0.75 | POLB (0.71) | EPHX2POLBHPGDALOX15KMT2A | |
| SCHEMBL28153695 | 0.75 | LRRK2 (0.54) | EPHX2POLBHPGDALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128455-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE S.A. (CH) | 2011-10-20 | — | — | WO | disclosed |