Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386366 | 0.73 | BRD4 (0.35) | APPTYRHRH3 | |
| SCHEMBL2117724 | 0.72 | TYR (0.58) | APPTYRCOMT | |
| SCHEMBL13555556 | 0.72 | TYR (0.41) | APPTYRHRH3COMTKDM4E | |
| SCHEMBL23139408 | 0.71 | APP (0.45) | APPTYRCOMTKDM4E | |
| SCHEMBL15100202 | 0.69 | APP (0.44) | APPTYRHPGD | |
| SCHEMBL15991636 | 0.68 | CCNC (0.49) | APPTYRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11926716 | 0.68 | TYR (0.49) | APPTYRCOMT | |
| SCHEMBL7931821 | 0.68 | COMT (0.56) | APPTYRCOMTKDM4E | |
| SCHEMBL2117658 | 0.67 | APP (0.41) | APPTYRCOMT | |
| SCHEMBL2117671 | 0.67 | TYR (0.43) | APPTYRCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532354-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5401734-A | MICROBIOCIDES | FUJISAWA PHAMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5244890-A | Treatment of infectious diseases | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0345671-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |