Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077539 | 0.75 | BRD4 (0.41) | BRD4 | |
| SCHEMBL9012839 | 0.73 | APP (0.42) | APPTYRHRH3 | |
| SCHEMBL13386368 | 0.69 | TYR (0.36) | APPTYR | |
| SCHEMBL18467745 | 0.62 | MAPT (0.39) | APPTYR | |
| SCHEMBL15100202 | 0.61 | APP (0.44) | BRD4APPTYR | |
| SCHEMBL15991636 | 0.60 | CCNC (0.49) | BRD4APPTYR | |
| SCHEMBL23139408 | 0.59 | APP (0.45) | APPTYR | |
| SCHEMBL4774585 | 0.59 | — | — | |
| SCHEMBL2117658 | 0.59 | APP (0.41) | APPTYR | |
| SCHEMBL13467616 | 0.58 | TYR (0.46) | APPTYRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
| US-9550733-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC. (CA) | 2017-01-24 | — | — | US | disclosed |
| US-20160083346-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | APOTEX TECHNOLOGIES INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-20150335626-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX INC. (CA) | 2015-11-26 | — | — | US | disclosed |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FLORIDA TURBINE TECHNOLOGIES, INC. | 2015-10-01 | — | — | US | disclosed |
| US-9073865-B2 | Fluorinated derivates of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC. (CA) | 2015-07-07 | — | — | US | disclosed |
| EP-2448922-B1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC (CA) | 2014-08-20 | — | — | EP | disclosed |
| CN-102712591-B | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC | 2014-06-25 | — | — | CN | disclosed |
| CN-103601673-A | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC | 2014-02-26 | — | — | CN | disclosed |
| US-20120270882-A1 | FLUORINATED DERIVATES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC. (CA) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083346-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | FH, FECH, FPGS | BRD4 3578/4885APP 2818/4885TYR 578/4885 |
| US-20150335626-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FH, FECH, TFRC | BRD4 3629/4885APP 3600/4885TYR 332/4885 |
| US-20120270882-A1 | FLUORINATED DERIVATES OF 3-HYDROXYPYRIDIN-4-ONES | FH, FECH, FTH1 | BRD4 3392/4885APP 3527/4885TYR 327/4885 |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | FH, FECH, FPGS | BRD4 3795/4885APP 3156/4885TYR 586/4885 |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | FH, FECH, FPGS | BRD4 4034/4885APP 2896/4885TYR 641/4885 |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FH, FECH, TFRC | BRD4 3629/4885APP 3600/4885TYR 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.