Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012930 | 1.00 | KCNH2 (0.48) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10504227 | 0.94 | KCNH2 (0.55) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10532770 | 0.94 | KCNH2 (0.55) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10504223 | 0.94 | KCNH2 (0.55) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL9624032 | 0.93 | KCNH2 (0.48) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL9624027 | 0.93 | KCNH2 (0.48) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL9013169 | 0.93 | ABCB11 (0.51) | KCNH2TDP1TSHRLMNAAPEX1 | |
| SCHEMBL9511476 | 0.93 | ABCB11 (0.51) | KCNH2TDP1TSHRLMNAAPEX1 | |
| SCHEMBL9013166 | 0.93 | ABCB11 (0.51) | KCNH2TDP1TSHRLMNAAPEX1 | |
| SCHEMBL9511482 | 0.93 | ABCB11 (0.51) | KCNH2TDP1TSHRLMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345671-B1 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5532354-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5401734-A | MICROBIOCIDES | FUJISAWA PHAMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5244890-A | Treatment of infectious diseases | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0345671-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |