Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744408 | 0.81 | MAPT (0.47) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL13555537 | 0.81 | MCHR1 (0.45) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1077539 | 0.79 | BRD4 (0.41) | BRD4CYP19A1ALDH1A1 | |
| SCHEMBL2118516 | 0.78 | MAPT (0.41) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL13555540 | 0.78 | MAPK14 (0.46) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL2115801 | 0.78 | SRD5A2 (0.51) | BRD4SRD5A1SRD5A2FOLH1 | |
| SCHEMBL13555553 | 0.78 | BRD4 (0.44) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL13386403 | 0.77 | MAPK14 (0.45) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL2468322 | 0.73 | PTGER1 (0.43) | CYP19A1 | |
| SCHEMBL987713 | 0.73 | PDK1 (0.41) | BRD4MAPK14SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532354-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |