SCHEMBL9013281

SCHEMBL9013281

CCCC1CCC(CCCCC2CCC(=O)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.42
TLR4 O00206 3/20 0.38
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C9 P11712 1/20 0.37
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
PKM P14618 1/20 0.35
CCR2 P41597 1/20 0.35
HTT P42858 2/20 0.34
MAPK1 P28482 1/20 0.34
MEN1 O00255 1/20 0.34
OPRM1 P35372 2/20 0.34
OPRL1 P41146 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013274 1.00 CYP1A2 (0.42) CYP1A2TLR4ALDH1A1KMT2ACYP2C9
SCHEMBL7912304 0.94 TLR4 (0.44) CYP1A2TLR4ALDH1A1KMT2ACYP2C9
SCHEMBL7912286 0.94 TLR4 (0.44) CYP1A2TLR4ALDH1A1KMT2ACYP2C9
SCHEMBL7912298 0.94 TLR4 (0.44) CYP1A2TLR4ALDH1A1KMT2ACYP2C9
SCHEMBL9013734 0.92 CYP1A2 (0.50) CYP1A2TLR4KMT2ACYP2C9LMNA
SCHEMBL7737007 0.92 CYP1A2 (0.50) CYP1A2TLR4KMT2ACYP2C9LMNA
SCHEMBL9013735 0.92 CYP1A2 (0.50) CYP1A2TLR4KMT2ACYP2C9LMNA
SCHEMBL7737003 0.92 CYP1A2 (0.50) CYP1A2TLR4KMT2ACYP2C9LMNA
SCHEMBL2888265 0.91 TLR4 (0.40) CYP1A2TLR4ALDH1A1KMT2ACYP2C9
SCHEMBL2888263 0.91 TLR4 (0.40) CYP1A2TLR4ALDH1A1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed