SCHEMBL7912286

SCHEMBL7912286

CCC[C@H]1CC[C@H](C2CCC(CCCCC3CCC(=O)CC3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 3/20 0.44
CYP1A2 P05177 4/20 0.39
ALDH1A1 P00352 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2C9 P11712 1/20 0.34
CCR2 P41597 1/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 2/20 0.33
PKM P14618 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
CHRM3 P20309 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
OPRM1 P35372 2/20 0.32
OPRL1 P41146 2/20 0.32
HTT P42858 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912298 1.00 TLR4 (0.44) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL7912304 1.00 TLR4 (0.44) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL9013274 0.94 CYP1A2 (0.42) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL9013281 0.94 CYP1A2 (0.42) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL8215701 0.90 TLR4 (0.51) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL1666552 0.90 TLR4 (0.51) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL1666553 0.90 TLR4 (0.51) TLR4CYP1A2ALDH1A1KMT2ACYP2C9
SCHEMBL6910065 0.89 CYP1A2 (0.46) TLR4CYP1A2KMT2ACYP2C9CCR2
SCHEMBL2892324 0.89 CYP1A2 (0.46) TLR4CYP1A2KMT2ACYP2C9CCR2
SCHEMBL13378068 0.89 CYP1A2 (0.46) TLR4CYP1A2KMT2ACYP2C9CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750028-B1 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2001-04-18 EP disclosed
US-5776367-A Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-07-07 US disclosed
EP-0750028-A2 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-12-27 EP disclosed