Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910127 | 0.88 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19MDM2MMP8 | |
| SCHEMBL8041382 | 0.78 | CES2 (0.44) | CYP1A2CYP2C9CYP2C19ELANECES2 | |
| SCHEMBL16880290 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19TRPM8LMNA | |
| SCHEMBL18810194 | 0.77 | CES2 (0.43) | CYP1A2CYP2C9CYP2C19ELANECES2 | |
| SCHEMBL7606942 | 0.77 | MEN1 (0.46) | CYP1A2CYP2C9CYP2C19MMP8ELANE | |
| SCHEMBL5179072 | 0.77 | CES2 (0.43) | CYP1A2CYP2C9CYP2C19ELANECES2 | |
| SCHEMBL8189631 | 0.77 | CES2 (0.43) | CYP1A2CYP2C9CYP2C19ELANECES2 | |
| SCHEMBL28683018 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19TRPM8LMNA | |
| Hydrochloric Acid SCHEMBL4650283 | 0.75 | CES2 (0.42) | CYP1A2CYP2C9CYP2C19ELANECES2 | |
| SCHEMBL8338411 | 0.73 | CES2 (0.40) | CYP1A2CYP2C9CYP2C19ELANECES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525506-A | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1996-06-11 | — | — | US | disclosed |