Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 2/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL9013643 | 0.98 | TYRO3 (0.41) | TYRO3NTRK2CLK4DYRK1BTDP2 | |
| Biphenyl SCHEMBL1712625 | 0.96 | TYRO3 (0.42) | TYRO3NTRK2CLK4DYRK1BTDP2 | |
| Hydantoin SCHEMBL29207375 | 0.85 | CRBN (0.42) | TYRO3NTRK2CLK4DYRK1BTDP2 | |
| Hydantoin SCHEMBL27574136 | 0.85 | CRBN (0.46) | ALDH1A1CYP11B1CYP11B2CRBNAHR | |
| Hydantoin SCHEMBL27362965 | 0.80 | TDP1 (0.44) | ALDH1A1CRBNHDAC8MMP2MMP3 | |
| Chlorobenzene SCHEMBL28430004 | 0.80 | TSHR (0.44) | GSK3AGSK3BCRBNHDAC8 | |
| Hydantoin SCHEMBL8638709 | 0.80 | — | — | |
| Hydantoin SCHEMBL753774 | 0.80 | — | — | |
| Hydantoin SCHEMBL8639680 | 0.80 | — | — | |
| 2-Phenylphenol SCHEMBL8682334 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PIM1KDRHDAC8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439903-A | Microvoidal silver diphenyl hydantoin ammonium complex for treating animal and plant tissue infections; wound healing agents, antiseptics | LASKER SIGMUND E (US) | 1995-08-08 | — | — | US | claimed |
| US-5571521-A | Composition containing silver ammonium phenytoin complex and a phenytoin and use of said composition | LASKER SIGMUND E (US) | 1996-11-05 | — | — | US | disclosed |