Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790107 | 0.81 | CYP1A2 (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8790438 | 0.76 | — | — | |
| SCHEMBL8792488 | 0.74 | MYC (0.41) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8791105 | 0.73 | MYC (0.39) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL9392461 | 0.73 | CHRM1 (0.38) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8789358 | 0.73 | MYC (0.39) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8789701 | 0.73 | MYC (0.42) | KDM4EPOLBNPC1RAB9AADORA1 | |
| SCHEMBL8790428 | 0.71 | — | — | |
| SCHEMBL2218274 | 0.71 | RPS6KB2 (0.50) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8790439 | 0.70 | MYC (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019467-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5488060-A | Substituted thiadiazoles, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |