Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.89 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.87 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014199 | 1.00 | PTGIR (0.89) | PTGIRTBXAS1PTGDRKDM4CPTGDR2 | |
| SCHEMBL9014426 | 0.94 | PTGIR (1.00) | PTGIRTBXAS1PTGDRPTGDR2 | |
| SCHEMBL9014454 | 0.93 | TBXAS1 (1.00) | PTGIRTBXAS1PTGDRKDM4CTBXA2R | |
| SCHEMBL9014466 | 0.93 | TBXAS1 (1.00) | PTGIRTBXAS1PTGDRKDM4CTBXA2R | |
| SCHEMBL9014277 | 0.92 | PTGIR (0.75) | PTGIRTBXAS1PTGDRKDM4CPTGDR2 | |
| SCHEMBL9014281 | 0.92 | PTGIR (0.75) | PTGIRTBXAS1PTGDRKDM4CPTGDR2 | |
| SCHEMBL9014513 | 0.87 | TBXAS1 (0.90) | PTGIRTBXAS1PTGDRTBXA2R | |
| SCHEMBL9014604 | 0.87 | TBXAS1 (0.90) | PTGIRTBXAS1PTGDRTBXA2R | |
| SCHEMBL9014420 | 0.86 | TBXAS1 (0.87) | PTGIRTBXAS1PTGDRKDM4CTBXA2R | |
| SCHEMBL9014417 | 0.86 | TBXAS1 (0.87) | PTGIRTBXAS1PTGDRKDM4CTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |