Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | PTGIR | P43119 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014270 | 1.00 | TBXAS1 (0.45) | TBXAS1PTGIRKDM4EKMT2ALMNA | |
| SCHEMBL9014467 | 0.95 | TBXAS1 (0.45) | TBXAS1PTGIRKDM4ELMNAALDH1A1 | |
| SCHEMBL9014457 | 0.95 | TBXAS1 (0.45) | TBXAS1PTGIRKDM4ELMNAALDH1A1 | |
| SCHEMBL9014272 | 0.88 | TBXAS1 (0.57) | TBXAS1PTGIRPTGDR | |
| SCHEMBL9014275 | 0.88 | TBXAS1 (0.57) | TBXAS1PTGIRPTGDR | |
| SCHEMBL9014292 | 0.87 | TBXAS1 (0.43) | TBXAS1PTGIRLMNAALDH1A1HTT | |
| SCHEMBL9014299 | 0.87 | TBXAS1 (0.43) | TBXAS1PTGIRLMNAALDH1A1HTT | |
| SCHEMBL9014548 | 0.87 | TBXAS1 (0.47) | TBXAS1PTGIRALDH1A1 | |
| SCHEMBL9014542 | 0.87 | TBXAS1 (0.47) | TBXAS1PTGIRALDH1A1 | |
| SCHEMBL9014210 | 0.83 | TBXAS1 (0.48) | TBXAS1PTGIRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |