SCHEMBL9014358

SCHEMBL9014358

COC(=O)CCC1CCCCC1O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA4 P22748 3/20 0.52
TSHR P16473 3/20 0.43
EPHX2 P34913 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDO2 P48775 1/20 0.34
CA6 P23280 2/20 0.33
KLK7 P49862 1/20 0.33
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8039891 0.88 CA1 (0.47) CA1CA2CA4TSHREPHX2
SCHEMBL6619684 0.80 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
SCHEMBL6643947 0.80 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
SCHEMBL6639313 0.80 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
SCHEMBL29069431 0.80 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
SCHEMBL6619689 0.80 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL6643943 0.79 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL6644945 0.79 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
SCHEMBL9056296 0.79 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL6641396 0.79 EPHX2 (0.41) TSHREPHX2SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533378-B1 Process for producing octahydrocoumarin or derivative thereof SUMITOMO CHEMICAL CO (JP) 1996-12-04 EP disclosed
EP-0551019-A1 Catalytic process of producing coumarin and derivatives thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-07-14 EP disclosed
EP-0533378-A1 Process for producing octahydrocoumarin or derivative thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-24 EP disclosed