Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24306422 | 0.82 | ALDH1A1 (0.32) | ALDH1A1HPGD | |
| SCHEMBL13895147 | 0.82 | EPHX2 (0.38) | EPHX2TSHRALDH1A1HSD17B10 | |
| SCHEMBL13867649 | 0.80 | EPHX2 (0.41) | EPHX2ALDH1A1 | |
| SCHEMBL13895126 | 0.79 | HCRTR1 (0.34) | EPHX2TSHRALDH1A1HSD17B10 | |
| SCHEMBL9014358 | 0.79 | CA1 (0.52) | EPHX2TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6619689 | 0.77 | EPHX2 (0.41) | EPHX2TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6639313 | 0.77 | EPHX2 (0.41) | EPHX2TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6643947 | 0.77 | EPHX2 (0.41) | EPHX2TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29069431 | 0.77 | EPHX2 (0.41) | EPHX2TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6619684 | 0.77 | EPHX2 (0.41) | EPHX2TSHRALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002514-A1 | UREA AND CARBAMIC ACID DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |