Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | PTGIR | P43119 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014441 | 1.00 | TBXAS1 (0.41) | TBXAS1PTGIRKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9014217 | 0.96 | TBXAS1 (0.39) | TBXAS1PTGIRKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9014215 | 0.96 | TBXAS1 (0.39) | TBXAS1PTGIRKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9014469 | 0.91 | TBXAS1 (0.42) | TBXAS1PTGIRKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9014464 | 0.91 | TBXAS1 (0.42) | TBXAS1PTGIRKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9014311 | 0.88 | TBXAS1 (0.43) | TBXAS1PTGIR | |
| SCHEMBL9014306 | 0.88 | TBXAS1 (0.43) | TBXAS1PTGIR | |
| SCHEMBL9014294 | 0.88 | TBXAS1 (0.40) | TBXAS1PTGIRKMT2A | |
| SCHEMBL9014287 | 0.88 | TBXAS1 (0.40) | TBXAS1PTGIRKMT2A | |
| SCHEMBL9014512 | 0.85 | PTGIR (0.40) | TBXAS1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |