Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014445 | 1.00 | PTGIR (0.62) | PTGIRPTGDRTBXAS1TBXA2RPPARG | |
| SCHEMBL9084302 | 0.93 | PTGIR (0.52) | PTGIRPTGDRTBXAS1TBXA2RPPARG | |
| SCHEMBL9084310 | 0.93 | PTGIR (0.52) | PTGIRPTGDRTBXAS1TBXA2RPPARG | |
| SCHEMBL9014528 | 0.86 | PTGIR (0.68) | PTGIRPTGDRTBXAS1TBXA2RLMNA | |
| SCHEMBL9014532 | 0.86 | PTGIR (0.68) | PTGIRPTGDRTBXAS1TBXA2RLMNA | |
| SCHEMBL4022778 | 0.84 | PTGIR (0.84) | PTGIRPTGDRTBXAS1TBXA2RMAPT | |
| SCHEMBL3771846 | 0.84 | PTGIR (0.84) | PTGIRPTGDRTBXAS1TBXA2RMAPT | |
| SCHEMBL3771841 | 0.84 | PTGIR (0.84) | PTGIRPTGDRTBXAS1TBXA2RMAPT | |
| SCHEMBL32681969 | 0.84 | PTGIR (0.84) | PTGIRPTGDRTBXAS1TBXA2RMAPT | |
| SCHEMBL9014224 | 0.84 | PTGIR (0.62) | PTGIRPTGDRTBXAS1TBXA2RNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |