Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.79 |
| ▸ | PTGIR | P43119 | 11/20 | 0.69 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014452 | 1.00 | TBXAS1 (0.79) | TBXAS1PTGIRKDM4CPTGDRSIGMAR1 | |
| SCHEMBL9014229 | 0.96 | TBXAS1 (0.77) | TBXAS1PTGIRKDM4CPTGDR | |
| SCHEMBL9014223 | 0.96 | TBXAS1 (0.77) | TBXAS1PTGIRKDM4CPTGDR | |
| SCHEMBL9014208 | 0.93 | TBXAS1 (0.69) | TBXAS1PTGIRKDM4CPTGDR | |
| SCHEMBL9014204 | 0.93 | TBXAS1 (0.69) | TBXAS1PTGIRKDM4CPTGDR | |
| SCHEMBL9014461 | 0.89 | TBXAS1 (0.67) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9014453 | 0.89 | TBXAS1 (0.67) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9014170 | 0.89 | TBXAS1 (0.76) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9014175 | 0.89 | TBXAS1 (0.76) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9014466 | 0.88 | TBXAS1 (1.00) | TBXAS1PTGIRKDM4CPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |