Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339917 | 0.91 | GPR84 (0.45) | GPR84FFAR1FFAR4TBXA2RPTGFR | |
| SCHEMBL25501505 | 0.81 | GPR84 (0.59) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL12991106 | 0.79 | GPR84 (0.68) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL26667095 | 0.78 | GPR84 (0.55) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL8577154 | 0.78 | GPR84 (0.61) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL23789287 | 0.77 | FFAR1 (0.67) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL4956318 | 0.77 | FFAR1 (0.67) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL7203318 | 0.77 | FFAR1 (0.67) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL2926826 | 0.77 | FFAR1 (0.67) | GPR84FFAR1FFAR4SPHK1PSMD14 | |
| SCHEMBL631940 | 0.77 | FFAR1 (0.67) | GPR84FFAR1FFAR4SPHK1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523495-A | REACTING KETONE OR ALDEHYDE WITH A DIHALOPROPENE IN PRESENCE OF ZINC POWDER, WATER AND ACID YIELDS A HALOALLYLCARBINOL WHICH CAN BE DEHALOGENATED WITH A BASE, NONEXPLOSIVE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0404077-B1 | Process for producing propargylcarbinol compounds | SUMITOMO CHEMICAL CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5258529-A | Dehydrohalogenation of corresponding alkene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0404077-A1 | Process for producing propargylcarbinol compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-12-27 | — | — | EP | disclosed |