Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014551 | 1.00 | PTGIR (0.54) | PTGIRPTGDRTBXAS1TDP1ALDH1A1 | |
| SCHEMBL9014585 | 0.92 | TBXAS1 (0.62) | PTGIRPTGDRTBXAS1ALDH1A1TBXA2R | |
| SCHEMBL9014587 | 0.92 | TBXAS1 (0.62) | PTGIRPTGDRTBXAS1ALDH1A1TBXA2R | |
| SCHEMBL9014609 | 0.83 | TBXAS1 (0.47) | PTGIRPTGDRTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9014612 | 0.83 | TBXAS1 (0.47) | PTGIRPTGDRTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9014183 | 0.82 | TBXAS1 (0.49) | PTGIRPTGDRTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9014179 | 0.82 | TBXAS1 (0.49) | PTGIRPTGDRTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9014498 | 0.81 | TBXAS1 (0.51) | PTGIRPTGDRTBXAS1ALDH1A1MRGPRX4 | |
| SCHEMBL9014494 | 0.81 | TBXAS1 (0.51) | PTGIRPTGDRTBXAS1ALDH1A1MRGPRX4 | |
| SCHEMBL9014205 | 0.80 | PTGIR (0.54) | PTGIRPTGDRTBXAS1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |