Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | DHFR | P00374 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064767 | 1.00 | CA2 (0.56) | CA2CA1CA12CA9LMNA | |
| SCHEMBL14497757 | 0.87 | CA2 (0.52) | CA2CA1CA12CA9LMNA | |
| SCHEMBL887827 | 0.87 | CA2 (0.52) | CA2CA1CA12CA9LMNA | |
| SCHEMBL13338129 | 0.87 | CA2 (0.52) | CA2CA1CA12CA9LMNA | |
| SCHEMBL8726202 | 0.84 | CA2 (0.46) | CA2CA1CA12CA9LMNA | |
| SCHEMBL7902186 | 0.84 | FOLH1 (0.58) | LMNAFOLH1GMNNALDH1A1CYP2D6 | |
| SCHEMBL4458797 | 0.84 | FOLH1 (0.58) | LMNAFOLH1GMNNALDH1A1CYP2D6 | |
| SCHEMBL27564186 | 0.83 | CA2 (0.75) | CA2CA1CA12CA9LMNA | |
| Hydrochloric Acid SCHEMBL7903946 | 0.82 | FOLH1 (0.57) | LMNAFOLH1GMNNALDH1A1CYP2D6 | |
| SCHEMBL7900436 | 0.82 | KMT2A (0.69) | LMNAFOLH1GMNNALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102099045-A | Attenuated oncolytic paramyxoviruses encoding avian cytokines | BAYER SCHERING PHARMA AG | 2011-06-15 | — | — | CN | disclosed |
| CN-101875919-A | Recombinant newcastle disease virus | BAYER SCHERING PHARMA AG | 2010-11-03 | — | — | CN | disclosed |
| CN-101056646-A | Recombinant newcastle disease virus | SCHERING AG (DE) | 2007-10-17 | — | — | CN | disclosed |
| EP-0745673-A2 | Catalytic antibody regulated prodrug therapy | ZENECA LIMITED (GB) | 1996-12-04 | — | — | EP | disclosed |