SCHEMBL9014772

SCHEMBL9014772

C1=C(CCC2=Cc3ccccc32)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARK7 Q99497 1/20 0.41
GPR84 Q9NQS5 1/20 0.35
CDC25B P30305 2/20 0.34
CDC25A P30304 1/20 0.34
PTPN1 P18031 2/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
HTR6 P50406 1/20 0.32
MAPT P10636 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.31
PTPRC P08575 1/20 0.31
THRB P10828 1/20 0.31
PKM P14618 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607496 0.85 PTPN1 (0.41) PARK7GPR84CDC25BCDC25APTPN1
SCHEMBL9377745 0.85 TDP1 (0.41) PARK7GPR84CDC25BCDC25APTPN1
SCHEMBL9376982 0.85 TDP1 (0.41) PARK7GPR84CDC25BCDC25APTPN1
SCHEMBL10608915 0.82 PTPN1 (0.50) PTPN1ALDH1A1BCHEACHECNR1
SCHEMBL10604576 0.80 PTPN1 (0.57) PTPN1ACHECNR1
SCHEMBL9320715 0.79 GPR84 (0.37) GPR84CDC25BCDC25AMTNR1AMTNR1B
SCHEMBL7276612 0.79 GPR84 (0.33) GPR84CDC25BCDC25AMTNR1AMTNR1B
SCHEMBL17601832 0.79 GPR84 (0.33) GPR84CDC25BCDC25AMTNR1AMTNR1B
SCHEMBL8717823 0.79 GPR84 (0.37) GPR84CDC25BCDC25AMTNR1AMTNR1B
SCHEMBL9629575 0.79 DPP4 (0.38) GPR84CDC25BCDC25AMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5416233-A Preparation of vinylsilane-benzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1995-05-16 US claimed
EP-0368025-A1 A method of polymerizing alpha-omega diynes THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP claimed
WO-1990004578-A1 A METHOD OF POLYMERIZING ALPHA-OMEGA DIYNES THE DOW CHEMICAL COMPANY (US) 1990-05-03 WO claimed
US-4877917-A CYCLIZATION WITH UNIVERSITY OF AKRON (US) 1989-10-31 US claimed
US-5567835-A Preparation of a vinylsiloxane-benzocylobutene from a hydrolyzable vinylsilane-benzocylobutene THE DOW CHEMICAL COMPANY (US) 1996-10-22 US disclosed
US-5416233-A Preparation of vinylsilane-benzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1995-05-16 US disclosed
US-5388328-A Forming metal layer, forming resist, filling windows in resist with conductor by plating, forming another windowed resist, filling windows with conductor, dissolving resist, filling spacings with varnish, curing HITACHI, LTD. (JP) 1995-02-14 US disclosed
US-5300735-A Interconnected multilayer boards and fabrication processes thereof HITACHI, LTD. (JP) 1994-04-05 US disclosed
EP-0368025-A1 A method of polymerizing alpha-omega diynes THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
WO-1990004578-A1 A METHOD OF POLYMERIZING ALPHA-OMEGA DIYNES THE DOW CHEMICAL COMPANY (US) 1990-05-03 WO disclosed
US-4877917-A CYCLIZATION WITH UNIVERSITY OF AKRON (US) 1989-10-31 US disclosed
US-4642329-A Prepolymer processing of arylcyclobutene monomeric compositions THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed