SCHEMBL9014916

SCHEMBL9014916

C=CCCNS(=O)(=O)CC(O)C(O)C(CC1CCCCC1)N[C@@H](Cc1c[nH]cn1)C(=O)NC(=O)C(Cc1ccccc1)CS(=O)(=O)C(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270874 0.92 REN (0.67) REN
SCHEMBL7426924 0.80 REN (0.60) REN
SCHEMBL7278484 0.79 REN (0.81) REN
SCHEMBL9014876 0.78 REN (0.64) REN
SCHEMBL9014890 0.78 REN (0.64) REN
SCHEMBL7280113 0.78 REN (0.64) REN
SCHEMBL9632624 0.78 REN (0.64) REN
SCHEMBL9226527 0.78 REN (0.68) REN
Remikiren SCHEMBL9556708 0.77 REN (0.76) REN
SCHEMBL6696481 0.77 REN (0.67) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545838-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1996-08-13 US disclosed
US-5098924-A Hypotensive agents and angiotensin II inhibitors E. R. SQUIBB & SONS, INC. (US) 1992-03-24 US disclosed