Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | PRF1 | P14222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015011 | 1.00 | HDAC1 (0.61) | HDAC1HDAC6HPGDPIM1PIM2 | |
| SCHEMBL29525335 | 0.83 | HDAC1 (0.60) | HDAC1HDAC6HPGDPIM1PIM2 | |
| SCHEMBL9177271 | 0.83 | CLK1 (0.63) | HDAC1HDAC6HPGDPIM1PIM2 | |
| SCHEMBL9177264 | 0.83 | CLK1 (0.63) | HDAC1HDAC6HPGDPIM1PIM2 | |
| SCHEMBL10750983 | 0.75 | GSK3B (0.68) | HPGDPIM1PIM2MAPTL3MBTL1 | |
| SCHEMBL10750988 | 0.75 | GSK3B (0.68) | HPGDPIM1PIM2MAPTL3MBTL1 | |
| SCHEMBL9208242 | 0.73 | PIM1 (0.52) | HDAC1HDAC6PIM1PIM2MAPT | |
| SCHEMBL29049326 | 0.69 | HPGD (0.59) | HPGDPIM1PIM2MAPTMEN1 | |
| SCHEMBL15828894 | 0.69 | HPGD (0.59) | HPGDPIM1PIM2MAPTMEN1 | |
| SCHEMBL2545596 | 0.68 | PIM1 (1.00) | HPGDPIM1PIM2TDP1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745069-A1 | PHARMACEUTICAL PIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1996-12-04 | — | — | EP | claimed |