Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 4/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226327 | 0.79 | IDO1 (0.39) | HSD17B10MEN1HTTKMT2AAHR | |
| SCHEMBL9226796 | 0.74 | HSD17B10 (0.42) | HSD17B10MEN1HTTKMT2AAHR | |
| SCHEMBL10446005 | 0.73 | HSD17B10 (0.39) | HSD17B10MEN1HTTKMT2AAHR | |
| SCHEMBL9339859 | 0.73 | PSD (0.41) | HSD17B10MEN1HTTKMT2APSD | |
| SCHEMBL9228083 | 0.72 | HSD17B10 (0.45) | HSD17B10MEN1HTTKMT2APSD | |
| SCHEMBL9226686 | 0.70 | VCAM1 (0.38) | HSD17B10MEN1HTTKMT2APSD | |
| SCHEMBL9225055 | 0.70 | MEN1 (0.54) | HSD17B10MEN1HTTKMT2APSD | |
| SCHEMBL9336163 | 0.69 | HSD17B10 (0.43) | HSD17B10MEN1HTTKMT2AAHR | |
| SCHEMBL9015111 | 0.69 | HSD17B10 (0.43) | HSD17B10MEN1HTTKMT2AAHR | |
| SCHEMBL9015099 | 0.69 | PSD (0.47) | HSD17B10MEN1HTTKMT2APSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |