Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.52 |
| ▸ | MAOA | P21397 | 17/20 | 0.52 |
| ▸ | MAOB | P27338 | 17/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903405 | 1.00 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL14762804 | 0.90 | KDM1A (0.43) | KDM1AMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL13731052 | 0.90 | KDM1A (0.43) | KDM1AMAOAMAOB | |
| SCHEMBL4739718 | 0.86 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL21066062 | 0.86 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL2766130 | 0.86 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL8041609 | 0.86 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL21066065 | 0.86 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL874954 | 0.86 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL15284779 | 0.86 | KDM1A (0.40) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621508-A1 | N-CARBOXYALKYL AURISTATINS AND THE USE THEREOF | Seattle Genetics, Inc. (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041805-A1 | N-CARBOXYALKYL AURISTATINS AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-04-05 | — | — | WO | disclosed |