Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12999669 | 0.97 | FASN (0.43) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL10052063 | 0.91 | ESR2 (0.41) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL28559153 | 0.91 | ESR2 (0.41) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL15256178 | 0.90 | ESR2 (0.40) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL9019618 | 0.89 | CYP3A4 (0.46) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL13263141 | 0.88 | FASN (0.42) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL12999670 | 0.88 | FASN (0.40) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL8932591 | 0.87 | KDM1A (0.40) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL8932667 | 0.86 | KDM1A (0.39) | FASNKDM1AFPR2CYP3A4CYP2C9 | |
| SCHEMBL8933414 | 0.85 | KDM1A (0.39) | FASNKDM1AFPR2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |