SCHEMBL10052063

SCHEMBL10052063

CCOc1ccc(-c2ccc(C3CCC(C)CC3)cc2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.41
KDM1A O60341 2/20 0.38
FPR2 P25090 6/20 0.36
FASN P49327 1/20 0.36
FGFR2 P21802 2/20 0.34
FGFR1 P11362 1/20 0.34
FFAR4 Q5NUL3 2/20 0.33
ALDH1A1 P00352 1/20 0.33
PTPRC P08575 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559153 1.00 ESR2 (0.41) ESR2KDM1AFPR2FASNFGFR2
SCHEMBL15256178 0.99 ESR2 (0.40) ESR2KDM1AFPR2FASNFGFR2
SCHEMBL9015050 0.91 FASN (0.45) ESR2KDM1AFPR2FASNFGFR2
SCHEMBL15849837 0.91 ESR2 (0.38) ESR2FPR2FASNFFAR4ALDH1A1
SCHEMBL26209577 0.90 KDM1A (0.39) KDM1AFPR2FGFR2FGFR1FFAR4
SCHEMBL17827784 0.90 KDM1A (0.39) KDM1AFPR2FGFR2FGFR1FFAR4
SCHEMBL19985315 0.90 RAB9A (0.39) ESR2FPR2FASNFFAR4CYP2C9
SCHEMBL13235448 0.90 ESR2 (0.37) ESR2KDM1AFPR2FASNFGFR2
SCHEMBL13235422 0.90 ESR2 (0.37) ESR2KDM1AFPR2FASNFGFR2
SCHEMBL16071781 0.90 FFAR4 (0.43) ESR2FFAR4ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
US-12024665-B2 Polymer-stabilized liquid crystal composition and use thereof BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-4273207-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-11-08 EP disclosed
WO-2023208801-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-11-02 WO disclosed
EP-3670503-B1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING SAME, AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD (CN) 2023-10-18 EP disclosed
EP-4261268-A1 LIQUID CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-10-18 EP disclosed
EP-4261267-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-10-18 EP disclosed
US-20230272282-A1 LC MIXTURES WITH NEGATIVE DELTA EPSILONCONTAINING CC-4-V1 AND COB(S)-N-OM MERCK PATENT GMBH (DE) 2023-08-31 US disclosed
US-20140293213-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2014-10-02 US disclosed
US-8840807-B2 Polymerizable compound JNC CORPORATION (JP) 2014-09-23 US disclosed
US-8834742-B2 Polymer-doped vertically-aligned nematic liquid crystals CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-09-16 US disclosed
US-20140239226-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2014-08-28 US disclosed
EP-2743331-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-06-18 EP disclosed
US-20140070142-A1 NEMATIC LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2014-03-13 US disclosed
US-20130277610-A1 LIQUID CRYSTAL COMPOUND SHOWING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20130230669-A1 DIFLUOROETHYLENEOXI DERIVATIVES, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-05 US disclosed
WO-2012016130-A2 POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-02-02 WO disclosed
US-7279202-B2 Liquid crystalline compound for vertical alignment and a liquid crystalline composition comprising the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-10-09 US disclosed