Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040414 | 1.00 | USP2 (0.47) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL9015087 | 1.00 | USP2 (0.47) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8040402 | 0.90 | FFAR1 (0.42) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL9015030 | 0.90 | FFAR1 (0.42) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8899697 | 0.88 | LTB4R (0.52) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8899706 | 0.88 | LTB4R (0.52) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8899724 | 0.88 | LTB4R (0.52) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8889121 | 0.86 | CYSLTR2 (0.45) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8889127 | 0.86 | CYSLTR2 (0.45) | USP2CYP3A4LTB4RLTB4R2FFAR1 | |
| SCHEMBL8029819 | 0.83 | CYP3A4 (0.47) | USP2CYP3A4LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539128-A | Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline | PFIZER INC. (US) | 1996-07-23 | — | — | US | disclosed |