Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043264 | 0.81 | CYP3A4 (0.66) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL15984861 | 0.80 | ALOX5 (0.56) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL841728 | 0.79 | CYP3A4 (1.00) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL30125417 | 0.79 | CYP3A4 (1.00) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL31580904 | 0.79 | CYP3A4 (0.62) | CYP3A4ALOX5NPC1RAB9A | |
| SCHEMBL25552185 | 0.79 | CYP3A4 (0.51) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL5042843 | 0.79 | CYP3A4 (0.51) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL5033238 | 0.79 | MAPT (0.54) | CYP3A4ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL13737643 | 0.78 | MAPT (0.53) | CYP3A4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31580570 | 0.78 | P4HTM (0.62) | CYP3A4ALOX5MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054845-C | Quinoline compounds | NOVARTIS AG (CH) | 2000-07-26 | — | — | CN | disclosed |
| US-5508408-A | LEUKOTRIENE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| CN-1105991-A | Quinoline compounds | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | CN | disclosed |
| EP-0643045-A1 | Quinoline derivatives as leukoriene antagonists | CIBA-GEIGY AG (CH) | 1995-03-15 | — | — | EP | disclosed |