Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015241 | 1.00 | POLB (0.44) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL12672699 | 0.92 | MEN1 (0.45) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL24998567 | 0.86 | MEN1 (0.41) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL14893329 | 0.84 | KMT2A (0.42) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10570044 | 0.82 | CYP3A4 (0.42) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL5466208 | 0.80 | KMT2A (0.46) | POLBALDH1A1MEN1KMT2AOPRL1 | |
| Hydrochloric Acid SCHEMBL7466665 | 0.79 | MEN1 (0.45) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8781588 | 0.79 | GAA (0.38) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27555623 | 0.78 | SIGMAR1 (0.45) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8663255 | 0.78 | OPRL1 (0.45) | POLBALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527923-A | Process for preparing enantiomerically pure diarylprolinols | BOEHRINGER INGELHEIM KG (DE) | 1996-06-18 | — | — | US | claimed |