⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888312 | 0.88 | — | — | |
| SCHEMBL2051101 | 0.81 | — | — | |
| SCHEMBL6266389 | 0.79 | — | — | |
| SCHEMBL10499973 | 0.78 | APP (0.31) | — | |
| SCHEMBL9277152 | 0.77 | — | — | |
| SCHEMBL1706668 | 0.76 | — | — | |
| SCHEMBL4138289 | 0.76 | — | — | |
| SCHEMBL6365020 | 0.76 | — | — | |
| SCHEMBL6689441 | 0.76 | — | — | |
| SCHEMBL1601967 | 0.76 | HTR7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512631-A | HOMO- OR COPOLYCARBONATES, AMORPHOUS POLYAMIDES AND THIOPHENYLALKYL ACRYLATES GRAFTED WITH STYRENE, HALO- OR ALKYL-SUBSTITUTED STYRENES HAVING PREFERRED GLASS TRANSITION TEMPERATURE AND REFRACTIVE INDEX | GENERAL ELECTRIC COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0581521-A2 | Thioaromatically substituted alkyl acrylates | GENERAL ELECTRIC COMPANY (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5274044-A | Grafted portion a styrene derivative | GENERAL ELECTRIC COMPANY | 1993-12-28 | — | — | US | disclosed |