Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015395 | 0.92 | ADRB3 (0.56) | ADRB3ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9015366 | 0.92 | ADRB3 (0.59) | ADRB3ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9015365 | 0.91 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015351 | 0.91 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015332 | 0.89 | ADRB3 (0.54) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015408 | 0.86 | ADRB3 (0.54) | ADRB3ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9015389 | 0.86 | ADRB3 (0.54) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015384 | 0.86 | ADRB3 (0.54) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9027131 | 0.86 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015345 | 0.86 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714883-A1 | Aryloxypropanolamine beta 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-05 | — | — | EP | claimed |
| US-5541204-A | Aryloxypropanolamine β 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0714883-A1 | Aryloxypropanolamine beta 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |