Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015332 | 0.91 | ADRB3 (0.54) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015395 | 0.90 | ADRB3 (0.56) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015345 | 0.90 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9027131 | 0.90 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015366 | 0.89 | ADRB3 (0.59) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9026756 | 0.88 | ADRB3 (0.54) | ADRB3ADRB2ADRB1AGTR1 | |
| SCHEMBL9015365 | 0.87 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015351 | 0.87 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015383 | 0.86 | ADRB3 (0.52) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9015384 | 0.86 | ADRB3 (0.54) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541204-A | Aryloxypropanolamine β 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0714883-A1 | Aryloxypropanolamine beta 3 adrenergic agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |