Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.79 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.79 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720259 | 0.96 | OPRK1 (0.73) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8719885 | 0.96 | OPRK1 (0.73) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8717698 | 0.96 | OPRK1 (0.88) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8720217 | 0.95 | OPRK1 (0.72) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8717427 | 0.93 | OPRK1 (0.69) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8722166 | 0.92 | OPRK1 (0.68) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8717389 | 0.89 | OPRK1 (0.79) | OPRK1OPRM1OPRD1CYP2D6 | |
| Asimadoline SCHEMBL8717354 | 0.88 | OPRK1 (1.00) | OPRK1OPRM1OPRD1CYP2D6 | |
| Asimadoline SCHEMBL6923822 | 0.88 | OPRK1 (1.00) | OPRK1OPRM1OPRD1CYP2D6 | |
| Asimadoline SCHEMBL13639176 | 0.88 | OPRK1 (1.00) | OPRK1OPRM1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532266-A | Acrylacetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |