Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015468 | 0.87 | TBXA2R (0.70) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9247878 | 0.86 | TBXA2R (0.58) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015411 | 0.84 | TBXA2R (0.60) | TBXA2RHDAC8TBXAS1PSEN1PSEN2 | |
| SCHEMBL7776609 | 0.84 | TBXA2R (0.59) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL7777964 | 0.82 | TBXA2R (0.54) | TBXA2RHDAC8TBXAS1PSEN1PSEN2 | |
| SCHEMBL9015465 | 0.81 | TBXA2R (0.60) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015509 | 0.79 | TBXA2R (0.55) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9253927 | 0.79 | TBXA2R (0.65) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL7776067 | 0.77 | TBXA2R (0.52) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9255293 | 0.77 | TBXA2R (0.56) | TBXA2RHDAC8TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648741-B1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR (FR) | 1996-12-18 | — | — | EP | disclosed |
| EP-0648741-A1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR ET COMPAGNIE (FR) | 1995-04-19 | — | — | EP | disclosed |