Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105728 | 0.87 | TBXA2R (0.56) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015468 | 0.86 | TBXA2R (0.70) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL7771706 | 0.86 | TBXA2R (0.61) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015454 | 0.84 | TBXA2R (0.60) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL7777991 | 0.83 | TBXA2R (0.53) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL7776067 | 0.82 | TBXA2R (0.52) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015411 | 0.82 | TBXA2R (0.60) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015465 | 0.80 | TBXA2R (0.60) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9253927 | 0.78 | TBXA2R (0.65) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9015509 | 0.78 | TBXA2R (0.55) | TBXA2RHDAC8TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864561-B1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| EP-0648741-B1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR (FR) | 1996-12-18 | — | — | EP | disclosed |
| EP-0648741-A1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR ET COMPAGNIE (FR) | 1995-04-19 | — | — | EP | disclosed |